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In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation

The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date, hematopoietic engraftment has mostly been achieved through the enforced expression of ectopic transcription factors. Here, we describe serum-...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Pearson, Stella, Cuvertino, Sara, Fleury, Maud, Lacaud, Georges, Kouskoff, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375940/
https://ncbi.nlm.nih.gov/pubmed/25660408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.003
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