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In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation

The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date, hematopoietic engraftment has mostly been achieved through the enforced expression of ectopic transcription factors. Here, we describe serum-...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Pearson, Stella, Cuvertino, Sara, Fleury, Maud, Lacaud, Georges, Kouskoff, Valerie
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375940/
https://ncbi.nlm.nih.gov/pubmed/25660408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.003
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