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SOX7-enforced expression promotes the expansion of adult blood progenitors and blocks B-cell development

During embryogenesis, the three SOXF transcription factors, SOX7, SOX17 and SOX18, regulate the specification of the cardiovascular system and are also involved in the development of haematopoiesis. The ectopic expression of SOX17 in both embryonic and adult blood cells enhances self-renewal. Likewi...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Cuvertino, Sara, Lacaud, Georges, Kouskoff, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967825/
https://ncbi.nlm.nih.gov/pubmed/27411892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.160070
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