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In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation

The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date, hematopoietic engraftment has mostly been achieved through the enforced expression of ectopic transcription factors. Here, we describe serum-...

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Hlavní autoři: Stella Pearson, Sara Cuvertino, Maud Fleury, Georges Lacaud, Valerie Kouskoff
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015-03-01
Edice:Stem Cell Reports
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213671115000247
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