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Properties of an Inward-Facing State of LeuT: Conformational Stability and Substrate Release
The leucine transporter (LeuT) is a bacterial homolog of the human monoamine transporters, which are important pharmaceutical targets. There are no high-resolution structures of the human transporters available; however, LeuT has been crystallized in several different conformational states. Recently...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375683/ https://ncbi.nlm.nih.gov/pubmed/25809252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.010 |
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