Probing the Huntingtin 1-17 Membrane Anchor on a Phospholipid Bilayer by Using All-Atom Simulations

Mislocalization and aggregation of the huntingtin protein are related to Huntington’s disease. Its first exon—more specifically the first 17 amino acids (Htt17)—is crucial for the physiological and pathological functions of huntingtin. It regulates huntingtin’s activity through posttranslational mod...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Côté, Sébastien, Binette, Vincent, Salnikov, Evgeniy S., Bechinger, Burkhard, Mousseau, Normand
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Proteins and Nucleic Acids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375615/
https://ncbi.nlm.nih.gov/pubmed/25762330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker