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Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

Ets-2, like its closely related homologue Ets-1, is a member of the Ets family of DNA binding transcription factors. Both proteins are subject to multiple levels of regulation of their DNA binding and transactivation properties. One such regulatory mechanism is the presence of an autoinhibitory modu...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Newman, Joseph A, Cooper, Christopher D. O., Aitkenhead, Hazel, Gileadi, Opher
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375503/
https://ncbi.nlm.nih.gov/pubmed/25670864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619270
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