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Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

Ets-2, like its closely related homologue Ets-1, is a member of the Ets family of DNA binding transcription factors. Both proteins are subject to multiple levels of regulation of their DNA binding and transactivation properties. One such regulatory mechanism is the presence of an autoinhibitory modu...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Newman, Joseph A, Cooper, Christopher D. O., Aitkenhead, Hazel, Gileadi, Opher
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375503/
https://ncbi.nlm.nih.gov/pubmed/25670864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619270
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