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R-Ras Protein Inhibits Autophosphorylation of Vascular Endothelial Growth Factor Receptor 2 in Endothelial Cells and Suppresses Receptor Activation in Tumor Vasculature

Abnormal angiogenesis is associated with a broad range of medical conditions, including cancer. The formation of neovasculature with functionally defective blood vessels significantly impacts tumor progression, metastasis, and the efficacy of anticancer therapies. Vascular endothelial growth factor...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Sawada, Junko, Li, Fangfei, Komatsu, Masanobu
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375470/
https://ncbi.nlm.nih.gov/pubmed/25645912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591511
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