Small GTPase R-Ras regulates Integrity and Functionality of Tumor Blood Vessels

We show that R-Ras, a small GTPase of the Ras family, is essential for the establishment of mature, functional blood vessels in tumors. The genetic disruption of R-Ras severely impaired the maturation processes of tumor vessels in mice. Conversely, the gain of function of R-Ras improved vessel struc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sawada, Junko, Urakami, Takeo, Li, Fangfei, Urakami, Akane, Zhu, Weiquan, Fukuda, Minoru, Li, Dean Y., Ruoslahti, Erkki, Komatsu, Masanobu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422514/
https://ncbi.nlm.nih.gov/pubmed/22897853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.06.013
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