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R-Ras Protein Inhibits Autophosphorylation of Vascular Endothelial Growth Factor Receptor 2 in Endothelial Cells and Suppresses Receptor Activation in Tumor Vasculature
Abnormal angiogenesis is associated with a broad range of medical conditions, including cancer. The formation of neovasculature with functionally defective blood vessels significantly impacts tumor progression, metastasis, and the efficacy of anticancer therapies. Vascular endothelial growth factor...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | J Biol Chem |
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Prif Awduron: | , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375470/ https://ncbi.nlm.nih.gov/pubmed/25645912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591511 |
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