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High Endothelial Venules Accelerate Naive T Cell Recruitment by Tumor Necrosis Factor-Mediated R-Ras Upregulation

Recruitment of naive T cells to lymph nodes is essential for the development of adaptive immunity. Upon pathogen infection, lymph nodes promptly increase the influx of naive T cells from the circulation in order to screen and prime the T cells. The precise contribution of the lymph node vasculature...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Sawada, Junko, Perrot, Carole Y., Chen, Linyuan, Fournier-Goss, Ashley E., Oyer, Jeremiah, Copik, Alicja, Komatsu, Masanobu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863135/
https://ncbi.nlm.nih.gov/pubmed/33159887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.10.009
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