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Prostaglandin E2 breaks down pericyte–endothelial cell interaction via EP1 and EP4-dependent downregulation of pericyte N-cadherin, connexin-43, and R-Ras

A close association between pericytes and endothelial cells (ECs) is crucial to the stability and function of capillary blood vessels and microvessels. The loss or dysfunction of pericytes results in significant disruption of these blood vessels as observed in pathological conditions, including canc...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Perrot, Carole Y., Herrera, Jose L., Fournier-Goss, Ashley E., Komatsu, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341885/
https://ncbi.nlm.nih.gov/pubmed/32636414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68019-w
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