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Prostaglandin E2 breaks down pericyte–endothelial cell interaction via EP1 and EP4-dependent downregulation of pericyte N-cadherin, connexin-43, and R-Ras

A close association between pericytes and endothelial cells (ECs) is crucial to the stability and function of capillary blood vessels and microvessels. The loss or dysfunction of pericytes results in significant disruption of these blood vessels as observed in pathological conditions, including canc...

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Vydáno v:Sci Rep
Hlavní autoři: Perrot, Carole Y., Herrera, Jose L., Fournier-Goss, Ashley E., Komatsu, Masanobu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341885/
https://ncbi.nlm.nih.gov/pubmed/32636414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68019-w
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