Viral Infection of Engrafted Human Islets Leads to Diabetes

Type 1 diabetes (T1D) is characterized by the destruction of the insulin-producing β-cells of pancreatic islets. Genetic and environmental factors both contribute to T1D development. Viral infection with enteroviruses is a suspected trigger for T1D, but a causal role remains unproven and controversi...

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Vydáno v:Diabetes
Hlavní autoři: Gallagher, Glen R., Brehm, Michael A., Finberg, Robert W., Barton, Bruce A., Shultz, Leonard D., Greiner, Dale L., Bortell, Rita, Wang, Jennifer P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
Immunology and Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375078/
https://ncbi.nlm.nih.gov/pubmed/25392246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1020
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