Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1

Constitutively active BCR-ABL kinase fusions are causative mutations in the pathogenesis of hematopoietic neoplasias including chronic myelogenous leukemia (CML). Although these fusions have been successfully targeted with kinase inhibitors, drug-resistance and relapse continue to limit long-term su...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ting, Pamela Y., Damoiseaux, Robert, Titz, Björn, Bradley, Kenneth A., Graeber, Thomas G., Fernández-Vega, Virneliz, Bannister, Thomas D., Chase, Peter, Nair, Reji, Scampavia, Louis, Hodder, Peter, Spicer, Timothy P., Colicelli, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374917/
https://ncbi.nlm.nih.gov/pubmed/25811598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121833
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados