Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119

GPR119 drug discovery efforts in the pharmaceutical industry for the treatment of type 2 diabetes mellitus (T2DM) and obesity, were initiated based on its restricted distribution in pancreas and GI tract, and its possible role in glucose homeostasis. While a number of lead series have emerged, the p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Assay Drug Dev Technol
Hauptverfasser: Nieto, Ainhoa, Fernández-Vega, Virneliz, Spicer, Timothy P., Sturchler, Emmanuel, Adhikari, Pramisha, Kennedy, Nicole, Mandat, Sean, Chase, Peter, Scampavia, Louis, Bannister, Thomas, Hodder, Peter, McDonald, Patricia H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2018
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065524/
https://ncbi.nlm.nih.gov/pubmed/30019946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2018.849
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