Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression

Recent genome wide association studies have linked tribbles pseudokinase 1 (TRIB1) to the risk of coronary artery disease (CAD). Based on the observations that increased expression of TRIB1 reduces secretion of VLDL and is associated with lower plasma levels of LDL cholesterol and triglycerides, hig...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nagiec, Marek M., Skepner, Adam P., Negri, Joseph, Eichhorn, Michelle, Kuperwasser, Nicolas, Comer, Eamon, Muncipinto, Giovanni, Subramanian, Aravind, Clish, Clary, Musunuru, Kiran, Duvall, Jeremy R., Foley, Michael, Perez, Jose R., Palmer, Michelle A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374785/
https://ncbi.nlm.nih.gov/pubmed/25811180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120295
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