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Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways

Spatio-temporal regulation of intracellular signalling networks is key to normal cellular physiology; dysregulation of which leads to disease. The family of three mammalian tribbles proteins has emerged as an important controller of signalling via regulating the activity of mitogen activated protein...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guan, Hongtao, Shuaib, Aban, Leon, David Davila De, Angyal, Adrienn, Salazar, Maria, Velasco, Guillermo, Holcombe, Mike, Dower, Steven K., Kiss-Toth, Endre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013389/
https://ncbi.nlm.nih.gov/pubmed/27600771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32667
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