NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) family member CIITA, which is recruited to SXY enhancers of MHCII promoters via a DNA-binding “enhanceosome” complex. NLRC5, another NLR protein, was recently found to control transcription of MHC class I (MHCI) genes. Howe...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Ludigs, Kristina, Seguín-Estévez, Queralt, Lemeille, Sylvain, Ferrero, Isabel, Rota, Giorgia, Chelbi, Sonia, Mattmann, Chantal, MacDonald, H. Robson, Reith, Walter, Guarda, Greta
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374748/
https://ncbi.nlm.nih.gov/pubmed/25811463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005088
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars