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Using Caenorhabditis elegans to Study Serpinopathies

Protein misfolding, polymerization, and/or aggregation are hallmarks of serpinopathies and many other human genetic disorders including Alzheimer’s, Huntington’s, and Parkinson’s disease. While higher organism models have helped shape our understanding of these diseases, simpler model systems, like...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Long, Olivia S., Gosai, Sager J., Kwak, Joon Hyeok, King, Dale E., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374434/
https://ncbi.nlm.nih.gov/pubmed/21683258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-386471-0.00013-4
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