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RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling

Chemokine signalling drives monocyte recruitment in atherosclerosis and aortic aneurysms. The mechanisms that lead to retention and accumulation of macrophages in the vascular wall remain unclear. Regulator of G-Protein Signalling-1 (RGS1) deactivates G-protein signalling, reducing the response to s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Patel, Jyoti, McNeill, Eileen, Douglas, Gillian, Hale, Ashley B., de Bono, Joseph, Lee, Regent, Iqbal, Asif J., Regan-Komito, Daniel, Stylianou, Elena, Greaves, David R., Channon, Keith M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374153/
https://ncbi.nlm.nih.gov/pubmed/25782711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7614
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