Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis

ABSTRACT: Chemokines (CK) provide directional cues that mediate the recruitment of leukocytes to sites of inflammation. Broad-spectrum blockade of the CC-CK family, using the vaccinia virus 35K protein, has been shown to cause a potent reduction of systemic inflammation in models of atherosclerosis,...

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Hlavní autoři: McNeill, Eileen, Iqbal, Asif J., Patel, Jyoti, White, Gemma E., Regan-Komito, Daniel, Greaves, David R., Channon, Keith M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206339/
https://ncbi.nlm.nih.gov/pubmed/25077938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1194-6
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