Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis

We previously reported that i) a Western diet increased levels of unsaturated lysophosphatidic acid (LPA) in small intestine and plasma of LDL receptor null (LDLR(−/−)) mice, and ii) supplementing standard mouse chow with unsaturated (but not saturated) LPA produced dyslipidemia and inflammation. He...

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Pubblicato in:J Lipid Res
Autori principali: Navab, Mohamad, Chattopadhyay, Arnab, Hough, Greg, Meriwether, David, Fogelman, Spencer I., Wagner, Alan C., Grijalva, Victor, Su, Feng, Anantharamaiah, G. M., Hwang, Lin H., Faull, Kym F., Reddy, Srinivasa T., Fogelman, Alan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373744/
https://ncbi.nlm.nih.gov/pubmed/25646365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M056614
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