Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid

We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR(−/−)) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but not saturated) L...

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Autors principals: Navab, Mohamad, Hough, Greg, Buga, Georgette M., Su, Feng, Wagner, Alan C., Meriwether, David, Chattopadhyay, Arnab, Gao, Feng, Grijalva, Victor, Danciger, Janet S., Van Lenten, Brian J., Org, Elin, Lusis, Aldons J., Pan, Calvin, Anantharamaiah, G. M., Farias-Eisner, Robin, Smyth, Susan S., Reddy, Srinivasa T., Fogelman, Alan M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826687/
https://ncbi.nlm.nih.gov/pubmed/24085744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M042051
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