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Bivalent Ligands Targeting Chemokine Receptor Dimerization: Molecular Design and Functional Studies

Increasing evidence has shown that chemokine receptors may form functional dimers with unique pharmacological profiles. A common practice to characterize such G protein-coupled receptor dimerization processes is to apply bivalent ligands as chemical probes which can interact with both receptors simu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Top Med Chem
Hauptverfasser: Arnatt, Christopher Kent, Zhang, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373595/
https://ncbi.nlm.nih.gov/pubmed/25159160
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