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Design and Synthesis of a Bivalent Ligand to Explore the Putative Heterodimerization of the Mu Opioid Receptor and the Chemokine Receptor CCR5

The bivalent ligand approach has been utilized not only to study the underlying mechanism of G protein-coupled receptors dimerization and/or oligomerization, but also aimed to enhance ligand affinity and/or selectivity for potential treatment of a variety of diseases by targeting this process. Subst...

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Bibliografiske detaljer
Udgivet i:Org Biomol Chem
Main Authors: Yuan, Yunyun, Arnatt, Christopher K., Li, Guo, Haney, Kendra M., Ding, Derong, Jacob, Joanna C., Selley, Dana E., Zhang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374901/
https://ncbi.nlm.nih.gov/pubmed/22354464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob06801j
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