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Design of bivalent ligands targeting putative GPCR dimers
G protein-coupled receptors (GPCRs) have been exploited as primary targets for drug discovery, and GPCR dimerization offers opportunities for drug design and disease treatment. An important strategy for targeting putative GPCR dimers is the use of bivalent ligands, which are single molecules that co...
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| Publicado no: | Drug Discov Today |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856001/ https://ncbi.nlm.nih.gov/pubmed/33075471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.10.006 |
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