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Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism
Measurements of the abundance of common metabolites in cultured embryonic stem (ES) cells revealed an unusual state with respect to one-carbon metabolism. These findings led to the discovery of copious expression of the gene encoding threonine dehydrogenase (TDH) in ES cells. TDH-mediated catabolism...
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| Publicado no: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373593/ https://ncbi.nlm.nih.gov/pubmed/19589965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1173288 |
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