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The Role of Thrombin and Cell Contractility in Regulating Clustering and Collective Migration of Corneal Fibroblasts in Different ECM Environments

PURPOSE. We previously reported that extracellular matrix composition (fibrin versus collagen) modulates the pattern of corneal fibroblast spreading and migration in 3-D culture. In this study, we investigate the role of thrombin and cell contractility in mediating these differences in cell behavior...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Miron-Mendoza, Miguel, Graham, Eric, Kivanany, Pouriska, Quiring, Jonathan, Petroll, W. Matthew
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373543/
https://ncbi.nlm.nih.gov/pubmed/25736789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16388
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