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The Role of Thrombin and Cell Contractility in Regulating Clustering and Collective Migration of Corneal Fibroblasts in Different ECM Environments

PURPOSE. We previously reported that extracellular matrix composition (fibrin versus collagen) modulates the pattern of corneal fibroblast spreading and migration in 3-D culture. In this study, we investigate the role of thrombin and cell contractility in mediating these differences in cell behavior...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Miron-Mendoza, Miguel, Graham, Eric, Kivanany, Pouriska, Quiring, Jonathan, Petroll, W. Matthew
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373543/
https://ncbi.nlm.nih.gov/pubmed/25736789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16388
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