ECM Stiffness Controls the Activation and Contractility of Corneal Keratocytes in Response to TGF-β1

After surgery or traumatic injury, corneal wound healing can cause a scarring response that stiffens the tissue and impairs ocular function. This fibrosis is caused in part by the activation of corneal keratocytes from a native mechanically quiescent state to an activated myofibroblastic state. This...

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發表在:Biophys J
Main Authors: Maruri, Daniel P., Miron-Mendoza, Miguel, Kivanany, Pouriska B., Hack, Joshua M., Schmidtke, David W., Petroll, W. Matthew, Varner, Victor D.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677126/
https://ncbi.nlm.nih.gov/pubmed/33080219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.040
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