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The Role of Thrombin and Cell Contractility in Regulating Clustering and Collective Migration of Corneal Fibroblasts in Different ECM Environments

PURPOSE. We previously reported that extracellular matrix composition (fibrin versus collagen) modulates the pattern of corneal fibroblast spreading and migration in 3-D culture. In this study, we investigate the role of thrombin and cell contractility in mediating these differences in cell behavior...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Miron-Mendoza, Miguel, Graham, Eric, Kivanany, Pouriska, Quiring, Jonathan, Petroll, W. Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373543/
https://ncbi.nlm.nih.gov/pubmed/25736789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16388
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