Affinity pulldown of γ-secretase and associated proteins from human and rat brain

γ-Secretase is a transmembrane protease complex responsible for the processing of a multitude of type 1 transmembrane proteins, including amyloid precursor protein (APP) and Notch. A functional complex is dependent on the assembly of four proteins: presenilin (PS), nicastrin, Aph-1 and Pen-2. Little...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Teranishi, Yasuhiro, Hur, Ji-Yeun, Welander, Hedvig, Frånberg, Jenny, Aoki, Mikio, Winblad, Bengt, Frykman, Susanne, Tjernberg, Lars O
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373488/
https://ncbi.nlm.nih.gov/pubmed/19754663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00907.x
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