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The Relative Influence of Metal Ion Binding Sites in the I-like Domain and the Interface with the Hybrid Domain on Rolling and Firm Adhesion by Integrin α(4)β(7)()

We examined the effect of conformational change at the β(7) I-like/hybrid domain interface on regulating the transition between rolling and firm adhesion by integrin α(4)β(7). An N-glycosylation site was introduced into the I-like/hybrid domain interface to act as a wedge and to stabilize the open c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, JianFeng, Takagi, Junichi, Xie, Can, Xiao, Tsan, Luo, Bing-Hao, Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373085/
https://ncbi.nlm.nih.gov/pubmed/15448154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M407773200
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