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Nuclear localization of SMN and FUS is not altered in fibroblasts from patients with sporadic ALS

BACKGROUND: Sporadic amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no established biological marker. Recent observation of a reduced number of gems (survival motor neuron protein (SMN)-positive nuclear bodies) in cells from patients with familial ALS and the mouse mod...

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Detalhes bibliográficos
Publicado no:Amyotroph Lateral Scler Frontotemporal Degener
Main Authors: Kariya, Shingo, Sampson, Jacinda B., Northrop, Lesley E., Luccarelli, Christopher M., Naini, Ali B., Re, Diane B., Hirano, Michio, Mitsumoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372808/
https://ncbi.nlm.nih.gov/pubmed/24809826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/21678421.2014.907319
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