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ShcA Regulates Thymocyte Proliferation through Specific Transcription Factors and a c-Abl-Dependent Signaling Axis
Signaling via the pre-T-cell receptor (pre-TCR), along with associated signals from Notch and chemokine receptors, regulates the β-selection checkpoint that operates on CD4(−) CD8(−) doubly negative (DN) thymocytes. Since many hematopoietic malignancies arise at the immature developmental stages of...
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| Publicado no: | Mol Cell Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372706/ https://ncbi.nlm.nih.gov/pubmed/25691660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01084-14 |
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