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The Adaptor Protein Shc Plays a Key Role During Early B Cell Development

The adaptor protein Shc is phosphorylated downstream of many cell surface receptors, including antigen and cytokine receptors. However, the role of Shc in B cell development has not been addressed. Here, through conditional expression of a dominant negative Shc mutant and conditional loss of Shc pro...

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Detalhes bibliográficos
Main Authors: Giles, Amber J., Bender, Timothy P., Ravichandran, Kodi S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847786/
https://ncbi.nlm.nih.gov/pubmed/19828641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902344
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