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ShcA regulates late stages of T cell development and peripheral CD4+ T cell numbers
T cell development in the thymus is a highly regulated process that critically depends upon productive signaling via the pre T cell Receptor (preTCR) at the β-selection stage, and via the TCR for selection from the CD4(+) CD8(+) double positive stage to the CD4 or CD8 single positive stage. ShcA is...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381912/ https://ncbi.nlm.nih.gov/pubmed/25595778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401728 |
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