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Ex vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells

Peripheral regulatory CD4(+) T cells (Treg cells) prevent maladaptive inflammatory responses to innocuous foreign antigens. Treg cell dysfunction has been linked to many inflammatory diseases, including allergic airway inflammation. Glucocorticoids that are used to treat allergic airway inflammation...

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Publicat a:PLoS One
Autors principals: Penberthy, Kristen Kelley, Buckley, Monica Weaver, Arandjelovic, Sanja, Ravichandran, Kodi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340387/
https://ncbi.nlm.nih.gov/pubmed/28267764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173386
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