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Autonomously Folding Protein Fragments Reveal Differences in the Energy Landscapes of Homologous RNases H

An important approach to understanding how a protein sequence encodes its energy landscape is to compare proteins with different sequences that fold to the same general native structure. In this work, we compare E. coli and T. thermophilus homologs of the protein RNase H. Using protein fragments, we...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Rosen, Laura E., Marqusee, Susan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372590/
https://ncbi.nlm.nih.gov/pubmed/25803034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119640
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