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Autonomously Folding Protein Fragments Reveal Differences in the Energy Landscapes of Homologous RNases H

An important approach to understanding how a protein sequence encodes its energy landscape is to compare proteins with different sequences that fold to the same general native structure. In this work, we compare E. coli and T. thermophilus homologs of the protein RNase H. Using protein fragments, we...

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Pubblicato in:PLoS One
Autori principali: Rosen, Laura E., Marqusee, Susan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372590/
https://ncbi.nlm.nih.gov/pubmed/25803034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119640
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