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A single mutation at residue 25 populates the folding intermediate of E. coli RNase H and reveals a highly dynamic partially-folded ensemble
Understanding the nature of partially folded intermediates transiently populated during protein folding is important for understanding both protein folding and misfolding. These ephemeral species, however, often elude direct experimental characterization. The well-characterized protein ribonuclease...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881687/ https://ncbi.nlm.nih.gov/pubmed/19505477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.05.084 |
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