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β-HPV 5 and 8 E6 Disrupt Homology Dependent Double Strand Break Repair by Attenuating BRCA1 and BRCA2 Expression and Foci Formation

Recent work has explored a putative role for the E6 protein from some β-human papillomavirus genus (β-HPVs) in the development of non-melanoma skin cancers, specifically β-HPV 5 and 8 E6. Because these viruses are not required for tumor maintenance, they are hypothesized to act as co-factors that en...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Wallace, Nicholas A., Robinson, Kristin, Howie, Heather L., Galloway, Denise A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372404/
https://ncbi.nlm.nih.gov/pubmed/25803638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004687
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