Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani

N-Myristoyltransferase (NMT) modulates protein function through the attachment of the lipid myristate to the N terminus of target proteins, and is a promising drug target in eukaryotic parasites such as Leishmania donovani. Only a small number of NMT substrates have been characterized in Leishmania,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Wright, Megan H., Paape, Daniel, Storck, Elisabeth M., Serwa, Remigiusz A., Smith, Deborah F., Tate, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372256/
https://ncbi.nlm.nih.gov/pubmed/25728269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.01.003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados