N-Myristoyltransferase from Leishmania donovani: Structural and Functional Characterisation of a Potential Drug Target for Visceral Leishmaniasis

N-Myristoyltransferase (NMT) catalyses the attachment of the 14-carbon saturated fatty acid, myristate, to the amino-terminal glycine residue of a subset of eukaryotic proteins that function in multiple cellular processes, including vesicular protein trafficking and signal transduction. In these pat...

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Main Authors: Brannigan, James A., Smith, Barbara A., Yu, Zhiyong, Brzozowski, Andrzej M., Hodgkinson, Michael R., Maroof, Asher, Price, Helen P., Meier, Franziska, Leatherbarrow, Robin J., Tate, Edward W., Smith, Deborah F., Wilkinson, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829124/
https://ncbi.nlm.nih.gov/pubmed/20036251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.032
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