טוען...
Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration
BACKGROUND: Genomic integration, an obligate step in the HIV-1 replication cycle, is blocked by the integrase inhibitor raltegravir. A consequence is an excess of unintegrated viral DNA genomes, which undergo intramolecular ligation and accumulate as 2-LTR circles. These circularized genomes are als...
שמור ב:
| הוצא לאור ב: | Retrovirology |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2015
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372172/ https://ncbi.nlm.nih.gov/pubmed/25808736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0153-9 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|