Lataa...

Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution

Agonist binding to G-protein–coupled receptors (GPCRs) triggers signal transduction cascades involving heterotrimeric G proteins as key players. A major obstacle for drug design is the limited knowledge of conformational changes upon agonist binding, the details of interaction with the different G p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Hillenbrand, Matthias, Schori, Christian, Schöppe, Jendrik, Plückthun, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371982/
https://ncbi.nlm.nih.gov/pubmed/25733868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417573112
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!