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Heterotrimeric G protein β(1)γ(2) subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane
Few experimental techniques can assess the orientation of peripheral membrane proteins in their native environment. Sum Frequency Generation (SFG) vibrational spectroscopy was applied to study the formation of the complex between G protein-coupled receptor (GPCR) kinase 2 (GRK2) and heterotrimeric G...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174637/ https://ncbi.nlm.nih.gov/pubmed/21876134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108236108 |
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