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Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy

The amyloid state of polypeptides is a stable, highly organized structural form consisting of laterally associated β-sheet protofilaments that may be adopted as an alternative to the functional, native state. Identifying the balance of forces stabilizing amyloid is fundamental to understanding the w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fitzpatrick, Anthony W. P., Vanacore, Giovanni M., Zewail, Ahmed H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371943/
https://ncbi.nlm.nih.gov/pubmed/25733888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502214112
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